Workflow How-Tos
- How to add plots and MS2 information to a Peptide report
- Digested Oligonucleotides workflow
- Byos Digested Oligonucleotide Workflow Setup Guide
- Intact Reconstruction Workflow
- Inspecting De Novo Sequencing (Supernovo) Results
- Charge Variant Analysis with Reconstruction How-To
Troubleshooting
- Byosphere - Unable to login: error while reading license data - incorrect format
- Issue Reporting for Byos/Byosphere desktop client
- Byonic Issue Reporting
- Byonic error message -99: No statistically significant identifications
- This application requires a Java Runtime Environment (JRE). Please install Java, either OpenJDK version > 11.0.2 or Oracle JRE version > 1.8.0
- Troubleshooting Byonic: Missing MS2 Spectra in .byrslt
Reporting
- Calculating DAR for Reduced ADCs
- Simplify Your Reporting with the New Fold Change Capability
- Oligonucleotide and Impurity UV-MS Quantitation
- Protein 3D file (pdb) configuration
- Fragment coverage map options
- Byos PTM Percent Modification Calculation
Intact
- Top-Down Analysis with Modified or Unnatural Amino Acids
- How to add additional protein identifications and delta masses to an Intact project
- Importing Delta masses from a CSV file
- How to reassign misassigned peaks in Intact
- Analyzing multiple ADC's in the same project
- Native MS Deconvolution Settings
Peptide How-Tos
- How to use Feature Finder in Peptides-based workflows
- Generating an in-silico list of peptide masses
- How to sequence different types of cyclic peptides
- Utilizing Inclusion Lists in Peptide Searches
- How to Make and Use the In-silico Disulfides CSV
- Asparagine Deamidation Quantified
Peptide Insights
- Cyclic Peptide Analysis
- Displaying MS2 fragment masses
- Crosslinked Peptide Pair Sequence and Score Designations in Byos
- Quantification of Modifications in the Peptide Workflows
- Byos PTM Quantitation Isotope Selection and {XIC area summed isoX normalized}
- How to Add MS Files After Project Creation in Peptide Workflows
Chromatogram & Released Glycans
- Released Glycan Fragmentation
- How to select a single or multiple peaks in the trace plot?
- Can the released glycan workflows be used to process data acquired in positive ionization mode?
- Glycan Cartoons in Byos
- Released Glycans Tips
- Chromatogram MS1 correlation colors
Application Notes
- Advancing Proteomic Analysis with Top-N Quantification: Combining Byos Muti-Protein Quantitation Module and GraphPad Prism
- A Middle-Level Approach for Characterization of the Fusion Protein Blinatumomab
- Enhancing Biosimilar Comparability: Integrating Byos with GraphPad Prism for Comprehensive Visual Analysis
- Intact Mass: Workflow Setup for Low MW (<10 kDa) Isotopically Resolved Peptides
- Intact Analysis of a Purified Therapeutic Protein Incorporating Top-Down Fragmentation
- Byonic: Mass Tolerance Settings
Byonic
- Top-down searching using Byonic™
- Byonic Modifications list options for MSMS search
- Discriminate Leucine and Isoleucine in Byonic
- Utilizing MS/MS Filtering
- How to run Protein Metrics Preview?
- Byonic MS/MS instrument parameters
Byos General
- Sorting of the samples in projects and reports
- How to create high quality image exports
- Creating a Custom Layout
- How Do I Export Plots for Manual Annotation and Editing?
- Creating and viewing customized workflows in Byos
- How do I know there is a software update available?
Byosphere General
- Opening, Editing, and Saving Byosphere Projects
- Byos to Byosphere User Transition Guide
- Byosphere Virtual and Desktop Clients
- User Type, Privileges and Roles in Byosphere
- 21 CFR Part 11 Compliance Capabilities
- Using Metadata and Deep Queries in Byosphere®
Installation & Activation
- APIs for Automation and External Integrations
- How to install Byonic into Thermo Fisher Scientific’s Proteome Discoverer software as a node?
- Byos System Requirements
- Activate your Byos license
- Offline activation
- Activation ID copies exceeds available copies
Articles in Chinese (中文文章)
- 解析糖肽搜库结果
- Janssen、Genentech和Amgen创建双特异性抗体中抗体链重组高度自动化的分析方法
- Byos报告简介
- 用于多聚糖和肽图分析的自动化数据处理
- 宿主细胞蛋白 (HCP)
- Protein Metrics电荷去卷积算法简介及应用