Currently Protein Metrics has a new Byos release at the end of every quarter. One can always check the downloads website to see if a new version is available. The password of the downloads site was delivered to you at the same time as licenses. If you don't have this info, please contact us.
Additionally, when you first open the software there is a splash screen that checks if an upgrade is available. This is not reliable however, because often times organization firewalls restrict this kind of a check as it needs to ping our website outside of the network. (And let's be honest, sometimes we forget to update it.)
While Byos desktop can be downloaded and installed easily, Byosphere upgrades involve more parties, such as IT and services organizations. For requesting an update to your Byosphere instance, please contact us.
Finally, we have a quarterly newsletter which lets users know that there is an upgrade available and what's new. You can sign up here: https://proteinmetrics.com/insights/