By default, PMI Intact Analysis uses peak intensity for quantitation, but can use area instead if Compute
areas of mass peaks is checked. This area is commonly used for antibody-drug conjugates. Width defines the width in daltons across which a peak is integrated to determine its area and is indicated by pink bars in the deconvolution plot.
Enabling Mass Area
During Project Creation: enable Mass Area by toggling Compute Areas of Mass Peaks to Yes in the Workflow Processing nodes tab under Mass area and intensity options
Post-project creation: enable Mass Area in the Analysis view by selecting Edit -> Mass area and intensity options
Reporting Mass Area
To change the quantitation calculation from intensity to mass area within the report, first select Show configuration. in the top left. The calculation aggregator options will appear. To change from intensity to mass area, click the drop-down option to the right of the rendering option: